Open Heart

Enhanced cardiovascular disease risk prediction using integrated machine learning models: a study from the UK Biobank cohort

Objective Cardiovascular diseases (CVD) remain the leading cause of mortality globally, necessitating early risk ...

Coding for a cure: Sewickley Academy student’s research reveals key differences in genetic mutations

Being invited to present research at an international academic conference is an honor for any seasoned professional. But for ...
Nature

Personalized mRNA vaccine induces strong, durable immunity in hard-to-treat breast cancer

In an experimental trial, a personalized mRNA vaccine was tested in 14 individuals with an aggressive form of breast cancer. It trained immune cells to target cancer-specific mutant proteins, inducing ...
eLife

Adaptation of an herbivorous arthropod to green tea plants by overcoming catechin defenses

Department of Chemistry and Biochemistry, University of South Carolina, Columbia, United States ...
eLife

EOLA1, a novel mitochondria-localized protein critical for heart functions via regulating mitochondrial translation

Mitochondria possess their own mRNA translation system, mediated by specialized mitoribosomes. Dysregulation of mitochondrial translation disrupts metabolic homeostasis and is linked to various ...
BMJ

A pathway-based approach investigating the genes encoding interleukin-1β, interleukin-6 and the interleukin-1 receptor antagonist provides new insight into the genetic ...

1 MRC/UCT Research Unit for Exercise Science and Sports Medicine, Department of Human Biology, University of Cape Town, Cape Town, South Africa 2 International Olympic Committee (IOC) Research Centre, ...