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Ozempic Improves Glycemic Control, Cuts Weight in Schizophrenia Patients

Low-dose semaglutide (Ozempic, Wegovy) improved glycemic control and weight outcomes in a randomized trial of adults whose ...
Thorax

Blood eosinophil-guided systemic corticosteroid duration in adults hospitalised for asthma exacerbation: a randomised, controlled, open-label, non-inferiority trial

Objective Systemic corticosteroids for 5–7 days are standard care for asthma exacerbations, but the optimal duration and ...
Canadian Medical Association Journal

A cluster randomized controlled trial of an electronic medical record–based pathway for pediatric asthma in primary care in Alberta

Background: Primary care physicians, who manage the care of most children with asthma, often do not optimally assess disease control, prescribe asthma controller medications, or provide family asthma ...
Medical Device and Diagnostic Industry (MD+DI)

Computer-Aided Clinical Trials for Medical Devices: From Research to Reality

The pharmaceutical and medical device industries stand at an inflection point. After decades of reliance on traditional ...
STAT

Boehringer Ingelheim prepares schizophrenia app for FDA submission after trial results

Boehringer Ingelheim plans to submit its app to treat under-addressed symptoms of schizophrenia for FDA clearance.
ascopubs.org

Historic Clinical Trial External Control Arm Provides Actionable GEN-1 Efficacy Estimate Before a Randomized Trial

To inform continued development of the novel immune agent GEN-1, we compared ovarian cancer patients' end points from a neoadjuvant single-arm phase IB study with those of similar historic clinical ...
STAT

Randomized controlled trials are the ‘gold standard’ of research — but a difficult fit for trans care

In order to provide gender-affirming care, clinicians must sometimes jump through unusual hoops. In Australia, for example, the government won’t subsidize testosterone treatment for a trans man ...