Intermediate filaments (IFs) are critical parts of the structure of cells. They are essential for both normal tissue structure and function. Enabling cells to withstand the stretch and pressure on the ...
This is a preview. Log in through your library . Abstract To screen invertebrate tissues for the possible expression of intermediate filaments (IFs), immunofluorescence microscopy with the monoclonal ...
This is a preview. Log in through your library . Abstract Mechanical tension influences tissue morphogenesis and the synthetic, mitotic, and motile behavior of cells. To determine the effects of ...
Biologists have found a unique version of a filament-forming protein in human cells that insects lack. Providing structural support and protection against such conditions as blistering, cataracts and ...
Living cells are constantly exposed to a wide variety of mechanical stresses: heart and lungs must withstand expansion and contraction; our skin must be resistant to tearing whilst retaining ...
Just as the skeleton and muscles move the human body and hold its shape, all the cells of the body are stabilised and moved by a cellular skeleton. Unlike our skeleton, this cellular skeleton is a ...
Glial Fibrillary Acidic Protein (GFAP) is a class-III intermediate filament that is mostly produced in astrocytic glial cells in the central nervous system. Astrocytes have important functions in ...
A number of spontaneous mutations in GFAP, encoding an astrocyte-specific intermediate filament protein, causes a neurodegenerative disease. It seems probable that these mutations effect gain of ...
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