As titers rise, the mass of the protein increases, but so does the downstream load. If a resin has a low Dynamic Binding Capacity (DBC), manufacturers are forced to use larger columns or more cycles, ...
The market is poised for growth (12.88% CAGR), driven by high demand for equipment due to capacity expansions, and the adoption of single-use systems, continuous bioprocessing, and digital twinsDublin ...
The current discussion of downstream bottlenecks arises from the ease with which up-stream activities generate protein and the desire for downstream operations to match upstream productivity. “In ...
Like all areas of bioprocessing, downstream purification has its own favored buzzwords—titers, bottlenecks, capacity, and others—meant to evoke a particular response depending on who is speaking or ...
With the recent FDA approval of the CAR T-cell therapies Kymriah ® from Novartis and Yescarta ® from Kite Pharma, there has been a renewed interest in bioprocessing and the manufacturing facilities ...
TORONTO--(BUSINESS WIRE)--Almonty Industries Inc. (“Almonty” or the “Company”) (TSX: AII / ASX: AII / OTCQX: ALMTF / Frankfurt: ALI) is pleased to announce it is investigating the construction of a ...
Keynote Presentation: A Generic Manufacturing Platform for Downstream Processing on Non-mab Proteins
The vast structural diversity of proteins is responsible for their functional versatility, but also makes their expression and purification a demanding task. Tagging proteins with affinity tags can ...
As a business owner or operations manager responsible for production, understanding the supply chain is essential to the success of your business. Any obstacle or impediment to the smooth flow of ...
Nova has commenced procurement of critical mining and processing equipment for its Estelle starter antimony mining operations and associated downstream antimony refinery at the deep-water Port ...
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