Collections of small molecules are used routinely in high-throughput screens to find new drug leads. In fact, from 1999 to 2008, 45 of the 50 Food and Drug Administration approvals for first-in-class ...

Chemists have synthesized a highly complex natural molecule through a new strategy of functionalizing normally inert carbon-hydrogen (C-H). The journal Science has published the breakthrough. Led by ...

The complex compound K₉N₅₆ was formed under unusual conditions: Potassium azide (KN₃) and molecular nitrogen (N₂) were compressed under a pressure more than 400,000 times higher than the pressure of ...

A major step toward simpler drug development has been taken at the University of Gothenburg. In a new study, researchers have developed stable boron-fluorine compounds that make it possible to ...

A metal-free boron-chemistry approach facilitates the selective replacement of hydrogen atoms in complex molecules, ...

A major step towards simpler drug development has been taken at the University of Gothenburg. In a new study, researchers ...

Explore how boron compounds are revolutionising drug development with new stable boron-fluorine compounds for better ...

A laboratory experiment at NASA’s Jet Propulsion Laboratory (JPL) in Pasadena, California, simulating the atmosphere of Saturn’s moon Titan suggests complex organic chemistry that could eventually ...

For the first time, MIT chemists have synthesized a fungal compound known as verticillin A, which was discovered more than 50 years ago and has shown potential as an anticancer agent. The compound has ...

Scientists report the first confirmed detection of thiepine, a complex sulfur-bearing molecule, in an interstellar cloud near the Milky Way’s center.

Chemists break down barriers between labs and institutions to join forces for a new way of doing organic synthesis. Chemists synthesized a highly complex natural molecule through a revolutionary ...