A hidden connection is stronger than an obvious one. —Heraclitus of Ephesus (535–475 BC) All surface-bound C3 convertases, regardless of origin, can induce the amplification branch of the alternative ...

Complement potentiates various forms of cancer therapy, including antibody-mediated cytotoxicity, vaccines and radiotherapy. Complement-dependent cytotoxicity can be improved by optimizing antibody ...

It was called ‘complement’ because it aided the antibacterial activity of antibodies. However, it is now known that the complement system can be activated early in an infection without the presence of ...

A research team at the Medical University of South Carolina reports in Cells that the complement system, part of the body's natural immune defenses, is a key driver of inflammatory responses that ...

Please provide your email address to receive an email when new articles are posted on . A protein known as granzyme K was recently shown to be a driver of inflammation by activating the complement ...

A thoughtful compliment can make your day…unless it’s backhanded, of course. A complement (spelled with an “e” instead of an “i”) can also be a good thing, but in a much different way. What’s the ...

Age-related macular degeneration is the most common cause of blindness in Western populations. Susceptibility is influenced by age and by genetic and environmental factors. Complement activation is ...