Signal transduction is the fundamental process by which cells convert external cues into tailored intracellular responses. Through a cascade of molecular events—beginning at the cell membrane with the ...
In a recently published review, a research team led by MedUni Vienna has highlighted a promising new approach to drug discovery. The focus is on the targeted modulation of certain intracellular ...
Researchers report a drug discovery strategy using tailor-made cyclic peptides to target β-arrestins, key regulators of ...
Edited by: Paul Smaglik Z. Liu, H. Hsu, D.V. Goeddel, M. Karin, "Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis, while NF-[kappa]B activation prevents cell ...
Edited by: James Kling P.A. Hoodless, T. Haerry, S. Abdollah, M. Stapleton, M.B. O'Connor, L. Attisano, J.L. Wrana, "MADR1, a MAD-related protein that functions in ...
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