Vaccines based on replication-defective adenoviral vectors are being developed for infectious agents and tumor-associated antigens. Early work focused on vaccines derived from a common human serotype ...
The human adenoviruses (Ads) comprise a group of 51 serologically distinct viruses. 1, 2 Among them, Ad vectors widely used for gene therapy are based on Ad serotype 5 (Ad5), which belongs to subgroup ...
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